As data centers rapidly transition from 400G to 800G and prepare for 1.6T networking, optical transceiver form factors have become a key design factor in network architecture. QSFP-DD, OSFP, and QSFP112 represent three distinct approaches to scaling bandwidth, balancing compatibility, thermal performance, and cost efficiency. This article provides a structured comparison of their electrical design, thermal behavior, and deployment scenarios. It also offers practical guidance for selecting the right form factor in modern AI, cloud, and HPC infrastructures.